Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | SORD | Q00796 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375519 | 0.88 | RIPK1 (0.41) | GPR119RIPK1LSSSORDPARP1 | |
| Bicarbonate SCHEMBL7371296 | 0.79 | GPR119 (0.38) | GPR119RIPK1LSSSORDPARP1 | |
| SCHEMBL7345833 | 0.74 | HRH3 (0.39) | HRH3 | |
| SCHEMBL7344376 | 0.74 | GPR119 (0.37) | GPR119RIPK1HRH3LSSSORD | |
| SCHEMBL7344262 | 0.72 | HRH3 (0.40) | HRH3 | |
| SCHEMBL7367199 | 0.71 | PARP1 (0.38) | HRH3PARP1 | |
| SCHEMBL7342864 | 0.69 | PARP1 (0.40) | HRH3PARP1 | |
| SCHEMBL8551353 | 0.68 | HTR2B (0.42) | GPR119RIPK1HRH3LSSSORD | |
| SCHEMBL7340536 | 0.67 | OGA (0.45) | HRH3 | |
| SCHEMBL16684964 | 0.67 | GPR119 (0.53) | GPR119RIPK1HRH3LSSSORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891359-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036899-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-09 | — | — | WO | disclosed |