Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755100 | 0.98 | ALDH1A1 (0.71) | ALDH1A1KMT2AGFERHTR1ALMNA | |
| SCHEMBL4496558 | 0.90 | TSHR (0.76) | KMT2AHTR1ATSHRMEN1SIGMAR1 | |
| Primaperone SCHEMBL310299 | 0.89 | TSHR (0.74) | KMT2AHTR1ATSHRMEN1SIGMAR1 | |
| Primaperone SCHEMBL364809 | 0.87 | TSHR (0.76) | KMT2AHTR1ATSHRMEN1SIGMAR1 | |
| SCHEMBL12123771 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KMT2AHTR1ALMNAMAPT | |
| SCHEMBL7352192 | 0.85 | DRD2 (0.62) | KMT2AHTR1ATSHRMEN1SIGMAR1 | |
| SCHEMBL8001854 | 0.84 | ALDH1A1 (0.70) | ALDH1A1KMT2AGFERLMNAMAPT | |
| Hydrochloric Acid SCHEMBL7929073 | 0.84 | ALDH1A1 (0.74) | ALDH1A1KMT2AHTR1ALMNAMAPT | |
| SCHEMBL9036253 | 0.84 | SIGMAR1 (0.52) | ALDH1A1KMT2AGFERHTR1AHTT | |
| SCHEMBL7354269 | 0.83 | DRD2 (0.63) | KMT2AHTR1ATSHRMEN1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |