SCHEMBL7344623

SCHEMBL7344623

CC(=O)C(O[SiH](c1ccccc1)c1ccccc1)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 6/20 0.33
TSHR P16473 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPT P10636 4/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
KCNN4 O15554 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
NAPRT Q6XQN6 2/20 0.31
DAO P14920 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 2/20 0.31
HDAC3 O15379 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9802325 0.89 ATM (0.37) ATML3MBTL1ALDH1A1TSHRHSD17B10
SCHEMBL8808719 0.86 ATM (0.35) ATML3MBTL1ALDH1A1TSHRHSD17B10
SCHEMBL10828688 0.82 TAS2R38 (0.31) ATML3MBTL1ALDH1A1ALOX15
SCHEMBL3858115 0.76 TRPA1 (0.35)
SCHEMBL9432002 0.75 TSHR (0.36) ATML3MBTL1ALDH1A1TSHRHSD17B10
SCHEMBL708401 0.73 TRPA1 (0.32) ATML3MBTL1ALDH1A1ALOX15
SCHEMBL7848050 0.72 MAPK1 (0.31) TSHR
SCHEMBL4766094 0.71 TRPA1 (0.36) ATML3MBTL1ALDH1A1LMNAALOX15
SCHEMBL7341479 0.71 TRPA1 (0.36) ATML3MBTL1ALDH1A1LMNAALOX15
SCHEMBL9569520 0.71 ATM (0.30) ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996031476-A1 AROMATIC HYDROXYETHERS RHONE-POULENC RORER LIMITED (GB) 1996-10-10 WO disclosed