Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802325 | 0.78 | ATM (0.37) | TSHRTP53ATML3MBTL1CYP2D6 | |
| SCHEMBL4766094 | 0.78 | TRPA1 (0.36) | ATML3MBTL1ALDH1A1 | |
| SCHEMBL7344623 | 0.75 | ATM (0.37) | TSHRATML3MBTL1ELANEKMT2A | |
| SCHEMBL5990675 | 0.73 | MMP1 (0.34) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5990687 | 0.73 | MMP1 (0.34) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL708401 | 0.73 | TRPA1 (0.32) | ATML3MBTL1ALDH1A1 | |
| SCHEMBL9735835 | 0.73 | ADRB2 (0.32) | TSHRTP53 | |
| SCHEMBL8808719 | 0.72 | ATM (0.35) | TSHRATML3MBTL1KMT2ACYP2C19 | |
| SCHEMBL7341479 | 0.71 | TRPA1 (0.36) | ATML3MBTL1ALDH1A1 | |
| SCHEMBL9569520 | 0.71 | ATM (0.30) | ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334328-A | Chiral azetidinone derivatives, and their use as dopes in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0520292-A1 | Chiral azetidinone derivatives and their use as dopants in liquid crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-30 | — | — | EP | disclosed |