Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10723938 | 0.86 | MEN1 (0.48) | HTR2AALOX5PTGS2PPARAPPARG | |
| SCHEMBL15174546 | 0.83 | TSHR (0.49) | HTR2AALOX5PTGS2PPARASPHK2 | |
| SCHEMBL9298934 | 0.78 | LIPG (0.41) | ALOX5PPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL7271422 | 0.77 | THRA (0.51) | ALDH1A1 | |
| SCHEMBL8907833 | 0.77 | THRA (0.51) | ALDH1A1 | |
| SCHEMBL9070266 | 0.77 | PPARG (0.55) | HTR2AALOX5PTGS2PPARAPPARG | |
| SCHEMBL9889155 | 0.77 | ADRA1A (0.64) | HTR2AALOX5PTGS2 | |
| SCHEMBL5133668 | 0.76 | ADRA1A (0.62) | HTR2AALOX5PTGS2 | |
| SCHEMBL14122353 | 0.76 | PPARG (0.57) | HTR2AALOX5PTGS2PPARAPPARG | |
| SCHEMBL10601156 | 0.76 | ADRA1A (0.62) | HTR2AALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |