Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 4/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344073 | 0.89 | PPARG (0.62) | PPARGACENPC1RAB9A | |
| SCHEMBL7348064 | 0.83 | CTSL (0.42) | FCER2MMP1ACENPC1RAB9A | |
| SCHEMBL7029937 | 0.83 | SMN1; SMN2 (0.47) | MMP1NPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL7343130 | 0.83 | CTSL (0.42) | FCER2MMP1ACEALDH1A1THRB | |
| SCHEMBL7020179 | 0.81 | MMP2 (0.51) | MMP1RAB9AMMP2MMP3MMP7 | |
| SCHEMBL7025425 | 0.80 | HSPA5 (0.63) | CYP2C9CYP2C19HSD17B10MMP2MMP3 | |
| SCHEMBL12354114 | 0.80 | HPGDS (0.51) | FCER2MMP1HPGDSPPARGCAPN1 | |
| SCHEMBL7340724 | 0.79 | PPARG (0.43) | FCER2MMP1PPARGCAPN1CTSB | |
| SCHEMBL7337025 | 0.79 | KLKB1 (0.52) | PPARGACE | |
| SCHEMBL7391206 | 0.79 | LMNA (0.48) | HPGDSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753410-B2 | ANALYZING THE PROCESSING OF AMYLOID PROTEIN PRECURSOR (APP); ALZHEIMER'S DISEASE; ENZYME INHIBITORS OF GAMMA-SECRETASE, A PROTEASE, AND INHIBITS PROTEOLYSIS OF PRESENILIN-1 ON WHICH THE SECRETASE ACTIVITY IS DEPENDENT | MERCK & CO., INC. | 2004-06-22 | — | — | US | disclosed |
| US-20020013276-A1 | Investigational compounds | MERCK & CO., INC. | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013276-A1 | Investigational compounds | CBR1, CBR3, CNR1 | FCER2 1494/4885MMP1 4016/4885HPGDS 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.