Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | USP14 | P54578 | 3/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344717 | 0.86 | ITGB3 (0.47) | ARCHRM4POLBCTSSCTSK | |
| SCHEMBL8686539 | 0.86 | CHRM4 (0.39) | ARCHRM4POLBCHRM2CTSS | |
| SCHEMBL7338620 | 0.84 | GPR119 (0.40) | GPR119MEN1 | |
| SCHEMBL7338598 | 0.84 | GPR119 (0.40) | GPR119MEN1 | |
| SCHEMBL7338609 | 0.84 | GPR119 (0.40) | GPR119MEN1 | |
| SCHEMBL7337986 | 0.82 | GPR119 (0.50) | ARCHRM4POLBGPR119USP14 | |
| SCHEMBL8783534 | 0.80 | PANK3 (0.36) | ARCHRM4POLBCTSSCTSK | |
| Acetic Acid SCHEMBL7345220 | 0.80 | CTSS (0.39) | ARCHRM4POLBCHRM2CTSS | |
| SCHEMBL8686522 | 0.78 | CHRM4 (0.38) | ARCHRM4CHRM2CTSSCTSK | |
| SCHEMBL8688902 | 0.77 | USP14 (0.42) | CHRM4POLBCTSSCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |