Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 14/20 | 0.52 |
| ▸ | MMP1 | P03956 | 13/20 | 0.52 |
| ▸ | MMP13 | P45452 | 13/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7349750 | 0.90 | MMP9 (0.54) | MMP9MMP1MMP13ADAM17BMP1 | |
| SCHEMBL7349061 | 0.89 | MMP1 (0.67) | MMP9MMP1MMP13ADAM17 | |
| SCHEMBL7350800 | 0.88 | BMP1 (0.54) | MMP9MMP1MMP13ADAM17BMP1 | |
| SCHEMBL7348771 | 0.87 | BMP1 (0.53) | MMP9MMP1MMP13ADAM17BMP1 | |
| Hydrochloric Acid SCHEMBL7343730 | 0.86 | MMP1 (0.54) | MMP9MMP1MMP13ADAM17BMP1 | |
| SCHEMBL7342996 | 0.85 | BMP1 (0.52) | MMP9MMP1MMP13ADAM17BMP1 | |
| SCHEMBL7349249 | 0.85 | BMP1 (0.52) | MMP9MMP1MMP13ADAM17BMP1 | |
| SCHEMBL7350757 | 0.85 | MMP13 (0.48) | MMP9MMP1MMP13ADAM17BMP1 | |
| Hydrochloric Acid SCHEMBL7350073 | 0.85 | MMP1 (0.48) | MMP9MMP1MMP13ADAM17BMP1 | |
| Hydrochloric Acid SCHEMBL7350069 | 0.84 | MMP9 (0.47) | MMP9MMP1MMP13ADAM17BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766672-B1 | ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS | NOVARTIS AG (CH) | 2000-10-04 | — | — | EP | disclosed |
| EP-0606046-B1 | Arylsulfonamido-substituted hydroxamic acids | CIBA GEIGY AG (CH) | 1997-10-08 | — | — | EP | disclosed |
| US-5646167-A | ADMINISTERED AS METALLOPROTEINASE INHIBITOR, ANTITUMOR OR ANTICARCINOGENIC AGENT | CIBA-GEIGY CORPORATION (US) | 1997-07-08 | — | — | US | disclosed |
| US-5552419-A | METALLOPROTEINASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| US-5506242-A | METALLOELASTASE INHIBITOR; TREATS EMPHYSEMA | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0606046-A1 | Arylsulfonamido-substituted hydroxamic acids | CIBA-GEIGY AG (CH) | 1994-07-13 | — | — | EP | disclosed |