Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343339 | 0.92 | AVPR2 (0.39) | WDR5DRD2BRPF1MAP3K7 | |
| SCHEMBL7338074 | 0.92 | DRD2 (0.46) | DRD2MAP3K7ADRA1DADRA1AADRA1B | |
| SCHEMBL7778595 | 0.90 | AVPR2 (0.42) | DRD2MAP3K7 | |
| SCHEMBL7342154 | 0.90 | NAMPT (0.38) | DRD2BRPF1MAP3K7BRD4ABL1 | |
| SCHEMBL7338566 | 0.90 | HDAC3 (0.37) | HDAC3HDAC1 | |
| SCHEMBL7337787 | 0.89 | ALDH1A1 (0.41) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7339388 | 0.89 | AVPR2 (0.42) | WDR5DRD2 | |
| SCHEMBL7338492 | 0.89 | BRPF1 (0.39) | BRPF1BRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL7347816 | 0.89 | TP53 (0.38) | HDAC3HDAC1 | |
| SCHEMBL7780810 | 0.89 | TP53 (0.42) | DRD2BRPF1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |