Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347212 | 0.83 | FFAR1 (0.45) | MMP1CACNA1BPSMB5RENOPRK1 | |
| SCHEMBL7337048 | 0.83 | CACNA1B (0.48) | MMP1MMP2MMP3CACNA1BPSMB5 | |
| SCHEMBL7338606 | 0.83 | CACNA1B (0.42) | MMP1MMP2MMP3CACNA1BIL1RN | |
| SCHEMBL7344639 | 0.82 | CACNA1B (0.45) | MMP1MMP2MMP3CACNA1BPSMB5 | |
| SCHEMBL7345788 | 0.81 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MMP1MMP2MMP3 | |
| SCHEMBL7348626 | 0.80 | MMP1 (0.43) | MMP1MMP2MMP3CACNA1BPSMB5 | |
| SCHEMBL7346468 | 0.79 | CACNA1B (0.40) | MMP1MMP2MMP3CACNA1BPSMB5 | |
| SCHEMBL7347666 | 0.77 | CACNA1B (0.46) | MMP1MMP2MMP3CACNA1BPSMB5 | |
| SCHEMBL7337467 | 0.77 | CACNA1B (0.47) | MMP1MMP2MMP3CACNA1BPSMB5 | |
| SCHEMBL7346017 | 0.76 | FFAR1 (0.45) | CACNA1BPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |