Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348159 | 0.92 | MMP1 (0.51) | MMP1MEN1KMT2AMMP3MMP10 | |
| SCHEMBL7344996 | 0.89 | MMP1 (0.58) | MMP1MEN1KMT2AMMP13SMN1; SMN2 | |
| SCHEMBL4783958 | 0.84 | MMP1 (0.79) | MMP1MEN1KMT2AMMP3MMP10 | |
| SCHEMBL4940266 | 0.81 | MMP1 (0.67) | MMP1MEN1KMT2AMMP13SMN1; SMN2 | |
| SCHEMBL7347132 | 0.78 | MMP1 (0.54) | MMP1MEN1KMT2AMMP3MMP13 | |
| SCHEMBL14302914 | 0.76 | MMP1 (0.66) | MMP1MMP3MMP13MMP2MMP9 | |
| SCHEMBL25130 | 0.76 | MMP1 (0.96) | MMP1MMP3MMP13MMP2MMP9 | |
| SCHEMBL7352297 | 0.76 | MMP1 (0.68) | MMP1MEN1KMT2AMMP3MMP13 | |
| SCHEMBL6813051 | 0.75 | MMP1 (0.94) | MMP1MMP3MMP13MMP2MMP9 | |
| SCHEMBL13556928 | 0.74 | MMP1 (0.81) | MMP1MEN1KMT2AMMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895988-B1 | Arylsulfonylamino hydroxamic acid derivatives | PFIZER PROD INC (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6107337-A | ANTIARTHRITIC AGENTS; ANTICARCINOGENIC AGENTS | PFIZER INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0895988-A1 | Arylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 1999-02-10 | — | — | EP | disclosed |