Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.51 |
| ▸ | MMP13 | P45452 | 9/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP10 | P09238 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345884 | 0.92 | MMP1 (0.58) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7344996 | 0.89 | MMP1 (0.58) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7352297 | 0.85 | MMP1 (0.68) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7347709 | 0.80 | MMP1 (0.56) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7357314 | 0.79 | MMP1 (0.47) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL26434 | 0.77 | MMP1 (0.83) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL4783958 | 0.76 | MMP1 (0.79) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7347598 | 0.76 | MMP1 (0.55) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL5413107 | 0.73 | MMP1 (0.68) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL4940266 | 0.73 | MMP1 (0.67) | MMP1MMP13MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895988-B1 | Arylsulfonylamino hydroxamic acid derivatives | PFIZER PROD INC (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6107337-A | ANTIARTHRITIC AGENTS; ANTICARCINOGENIC AGENTS | PFIZER INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0895988-A1 | Arylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 1999-02-10 | — | — | EP | disclosed |