Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352509 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MMP2MMP9RAB9AMAPT | |
| SCHEMBL7352983 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MMP2MMP9RAB9AHSD17B10 | |
| SCHEMBL7352123 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTHSD17B10POLBHDAC1 | |
| SCHEMBL7349016 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MMP2MMP9RAB9AHSD17B10 | |
| SCHEMBL7347936 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HSD17B10HDAC1 | |
| SCHEMBL12279346 | 0.76 | ALDH1A1 (0.44) | ALDH1A1RAB9AMAPTGSK3BCHRM5 | |
| SCHEMBL15092409 | 0.76 | ALDH1A1 (0.44) | ALDH1A1RAB9AMAPTGSK3BCHRM5 | |
| SCHEMBL15092407 | 0.76 | ALDH1A1 (0.44) | ALDH1A1RAB9AMAPTGSK3BCHRM5 | |
| SCHEMBL7352732 | 0.76 | RAB9A (0.46) | ALDH1A1MMP2MMP9RAB9AMMP1 | |
| SCHEMBL7357652 | 0.73 | NPSR1 (0.39) | TSHRSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |