Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352983 | 0.85 | ALDH1A1 (0.44) | ALDH1A1HSD17B10SMN1; SMN2POLBPKM | |
| SCHEMBL7352509 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HSD17B10SMN1; SMN2POLBPKM | |
| SCHEMBL7347524 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HSD17B10SMN1; SMN2POLBPKM | |
| SCHEMBL7352714 | 0.78 | PER2 (0.38) | ALDH1A1 | |
| SCHEMBL7351114 | 0.77 | L3MBTL1 (0.42) | ALDH1A1HSD17B10SMN1; SMN2POLBPKM | |
| SCHEMBL7345910 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HSD17B10SMN1; SMN2POLBPKM | |
| SCHEMBL7348333 | 0.73 | HTR1A (0.42) | ACHE | |
| SCHEMBL7348069 | 0.73 | SMN1; SMN2 (0.54) | ALDH1A1HSD17B10SMN1; SMN2POLBPKM | |
| SCHEMBL9485569 | 0.71 | ALDH1A1 (0.57) | ALDH1A1HSD17B10SMN1; SMN2POLBPKM | |
| SCHEMBL7356102 | 0.71 | CYP3A4 (0.37) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |