Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347936 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HSD17B10HDAC1HDAC6APLNR | |
| SCHEMBL7353468 | 0.84 | ALDH1A1 (0.34) | ALDH1A1HSD17B10MAPTPOLBMIF | |
| SCHEMBL7345910 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MAPTHDAC1POLB | |
| SCHEMBL7347075 | 0.81 | P2RX7 (0.37) | ALDH1A1HSD17B10MAPTP2RX7APLNR | |
| SCHEMBL7357652 | 0.78 | NPSR1 (0.39) | — | |
| SCHEMBL7350624 | 0.76 | PER2 (0.37) | ALDH1A1MAPTPOLBHTT | |
| SCHEMBL7346953 | 0.75 | ADRB2 (0.42) | HSD17B10MAPTAPLNRDGAT1PDE2A | |
| SCHEMBL7356312 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10GAAMAPTPOLB | |
| SCHEMBL11899944 | 0.73 | PDE2A (0.45) | HSD17B10MAPTAPLNRPOLBDGAT1 | |
| SCHEMBL7350207 | 0.73 | SIGMAR1 (0.34) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |