Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346517 | 0.76 | TSHR (0.39) | MAPT | |
| SCHEMBL29495188 | 0.71 | MAPT (0.52) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL7350399 | 0.70 | LMNA (0.41) | MAPT | |
| SCHEMBL8083071 | 0.69 | MAPT (0.40) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL19453500 | 0.69 | LOXL2 (0.42) | — | |
| SCHEMBL29495251 | 0.69 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL29495273 | 0.69 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL29495158 | 0.67 | MAPT (0.44) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL10066486 | 0.67 | GRIK1 (0.52) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL27850446 | 0.64 | GAA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318975-A | 5-pyrimdineamine derivatives | BERLEX LABORATORIES, INC. (US) | 1994-06-07 | — | — | US | disclosed |