Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346962 | 0.81 | ITGB1 (0.47) | SENP1LMNAITGB1ITGA5 | |
| SCHEMBL6774133 | 0.79 | TP53 (0.45) | ALDH1A1MAPTLMNAITGB1ITGA5 | |
| SCHEMBL7346968 | 0.79 | KCNK3 (0.45) | SENP1MAPTLMNAITGB1ITGA5 | |
| SCHEMBL7345956 | 0.79 | KCNK3 (0.45) | SENP1MAPTLMNAITGB1ITGA5 | |
| SCHEMBL6774132 | 0.76 | GPR139 (0.44) | MAPTITGB1ITGA5 | |
| SCHEMBL6774128 | 0.76 | GPR139 (0.44) | MAPTITGB1ITGA5 | |
| SCHEMBL6776895 | 0.76 | ITGB3 (0.47) | ITGB1ITGA5 | |
| SCHEMBL6776891 | 0.76 | ITGB3 (0.47) | ITGB1ITGA5 | |
| SCHEMBL6772589 | 0.75 | RAB9A (0.51) | ALDH1A1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6772591 | 0.75 | RAB9A (0.51) | ALDH1A1HPGDMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |