Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346968 | 1.00 | KCNK3 (0.45) | KCNK3KCNK9F2RHTTL3MBTL1 | |
| SCHEMBL7350667 | 0.92 | KCNK3 (0.44) | KCNK3KCNK9HTTL3MBTL1ITGB1 | |
| SCHEMBL7350687 | 0.92 | KCNK3 (0.44) | KCNK3KCNK9HTTL3MBTL1ITGB1 | |
| SCHEMBL7338982 | 0.91 | SENP1 (0.46) | KCNK3KCNK9HTTL3MBTL1ITGB1 | |
| SCHEMBL7338973 | 0.91 | SENP1 (0.46) | KCNK3KCNK9HTTL3MBTL1ITGB1 | |
| SCHEMBL7383607 | 0.82 | KCNK3 (0.48) | KCNK3KCNK9L3MBTL1SENP1MAPT | |
| SCHEMBL7383610 | 0.82 | KCNK3 (0.48) | KCNK3KCNK9L3MBTL1SENP1MAPT | |
| SCHEMBL7346962 | 0.80 | ITGB1 (0.47) | ITGB1ITGA5SENP1LMNAGPR139 | |
| SCHEMBL7345963 | 0.79 | SENP1 (0.46) | F2RITGB1ITGA5SENP1MAPT | |
| SCHEMBL6776895 | 0.78 | ITGB3 (0.47) | ITGB1ITGA5TAOK1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |