Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 6/20 | 0.72 |
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.70 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.59 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348393 | 0.90 | SGMS2 (0.65) | GCKSGMS2CXCR2GAANPC1 | |
| SCHEMBL5279225 | 0.84 | KMT2A (0.69) | GCKHCAR3GAANPC1MEN1 | |
| SCHEMBL27613370 | 0.82 | SGMS2 (0.65) | GCKSGMS2CXCR2GAANPC1 | |
| SCHEMBL8203327 | 0.82 | SGMS2 (0.82) | SGMS2GAANPC1MEN1KMT2A | |
| SCHEMBL30322922 | 0.82 | SGMS2 (1.00) | SGMS2GAANPC1MEN1KMT2A | |
| SCHEMBL17551827 | 0.82 | SGMS2 (1.00) | SGMS2GAANPC1MEN1KMT2A | |
| SCHEMBL5237475 | 0.81 | HCAR3 (0.59) | GCKHCAR3CXCR2GAANPC1 | |
| SCHEMBL1791977 | 0.81 | GCK (1.00) | GCKHCAR3CXCR2MEN1KMT2A | |
| SCHEMBL27437443 | 0.78 | GCK (0.55) | GCKHCAR3CXCR2GAAMEN1 | |
| SCHEMBL875474 | 0.77 | SGMS2 (1.00) | SGMS2GAANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |