Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.65 |
| ▸ | GCK | P35557 | 3/20 | 0.62 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345966 | 0.90 | GCK (0.72) | SGMS2GCKCXCR2GAAMEN1 | |
| SCHEMBL2653573 | 0.87 | GCK (0.55) | SGMS2GCKCXCR2GAAMEN1 | |
| SCHEMBL8205171 | 0.83 | SGMS2 (0.76) | SGMS2GAAMEN1KMT2ANPC1 | |
| SCHEMBL2652506 | 0.82 | GCK (0.81) | GCKCXCR2MEN1KMT2A | |
| SCHEMBL27613370 | 0.80 | SGMS2 (0.65) | SGMS2GCKCXCR2GAAMEN1 | |
| SCHEMBL8022247 | 0.80 | GABRA5 (0.52) | GCKCXCR2GAAMEN1KMT2A | |
| SCHEMBL14505828 | 0.80 | GCK (0.60) | GCKCXCR2MEN1KMT2ANPC1 | |
| SCHEMBL752452 | 0.79 | MEN1 (0.60) | GCKCXCR2GAAMEN1KMT2A | |
| SCHEMBL17551827 | 0.79 | SGMS2 (1.00) | SGMS2GAAMEN1KMT2ANPC1 | |
| SCHEMBL8827562 | 0.79 | RAB9A (0.65) | GAAMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |