Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.49 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347118 | 0.88 | CACNA2D1 (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CCYP1A2 | |
| SCHEMBL8256016 | 0.86 | LMNA (0.52) | ALPLPTBP1ALOX15CYP1A2CYP2C19 | |
| SCHEMBL7347657 | 0.86 | LMNA (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CALOX15 | |
| SCHEMBL7339023 | 0.86 | CACNA2D1 (0.65) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL7346581 | 0.84 | MAPT (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CMEN1 | |
| SCHEMBL7340551 | 0.82 | CACNA2D1 (0.56) | CACNA2D1CACNA1BCACNB1CACNA1CMEN1 | |
| SCHEMBL7339537 | 0.81 | CACNA2D1 (0.56) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL7342475 | 0.79 | CACNA2D1 (0.54) | CACNA2D1CACNA1BCACNB1CACNA1CMEN1 | |
| Hydrochloric Acid SCHEMBL7341072 | 0.78 | CACNA2D1 (0.53) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL7340694 | 0.78 | MAPT (0.44) | CACNA2D1CACNA1BCACNB1CACNA1CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117525-B | Organic luminescent material containing triazinyl and anilino, preparation method, application and device thereof | 武汉尚赛光电科技有限公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-108698992-A | 2- cyano isoindoline derivatives for treating cancer | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108218763-A | A kind of phenyl indene compounds, organic electroluminescence device and display device | 阜阳欣奕华材料科技有限公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-105453306-B | Binder for nonaqueous electricity storage element and nonaqueous electricity storage element | 协立化学产业株式会社 | 2018-02-13 | — | — | CN | disclosed |
| CN-102482277-B | Epidermal growth factor receptor inhibitor and the method for treating obstacle | 达纳-法伯癌症研究所有限公司 | 2017-09-19 | — | — | CN | disclosed |
| CN-105263968-B | Colored curable resin composition | 东友精细化工有限公司 | 2017-08-22 | — | — | CN | disclosed |
| CN-102736412-B | Photosensitive composition | 住友化学株式会社 | 2017-05-31 | — | — | CN | disclosed |
| CN-102503881-B | Optically active tryptamine derivative and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2013-08-07 | — | — | CN | disclosed |
| CN-102503881-A | Optically active tryptamine derivative and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2012-06-20 | — | — | CN | disclosed |
| CN-100534990-C | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-02 | — | — | CN | disclosed |
| CN-1610678-A | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2005-04-27 | — | — | CN | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |