Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.41 |
| ▸ | ITGAV | P06756 | 3/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 2/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 8/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355053 | 1.00 | ITGB3 (0.41) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7345142 | 0.86 | CYP3A4 (0.43) | ITGB3ITGAVSUCNR1MAPT | |
| SCHEMBL7353534 | 0.84 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7346263 | 0.82 | ITGB3 (0.46) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7344378 | 0.73 | MEN1 (0.62) | NPSR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7345450 | 0.73 | ITGB3 (0.48) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7345936 | 0.73 | ITGB3 (0.46) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7146701 | 0.71 | MEN1 (0.56) | SUCNR1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7146704 | 0.71 | MEN1 (0.56) | SUCNR1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7345928 | 0.71 | PTGER4 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570507-A4 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORP (US) | 1994-09-21 | — | — | EP | disclosed |
| EP-0570507-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-24 | — | — | EP | disclosed |
| WO-1992013552-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-20 | — | — | WO | disclosed |