Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.52 |
| ▸ | CACNB1 | Q02641 | 5/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339023 | 0.87 | CACNA2D1 (0.65) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL1361808 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HTTLMNAKMT2AL3MBTL1 | |
| SCHEMBL7339537 | 0.82 | CACNA2D1 (0.56) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL7341072 | 0.81 | CACNA2D1 (0.53) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL17147663 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBHTTLMNAKMT2A | |
| SCHEMBL7342475 | 0.80 | CACNA2D1 (0.54) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL27959322 | 0.80 | CHRM2 (0.47) | ALDH1A1HTTLMNAKMT2ASIRT6 | |
| SCHEMBL7346027 | 0.79 | CACNA2D1 (0.53) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7339671 | 0.79 | CACNA2D1 (0.53) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7342378 | 0.78 | CACNA2D1 (0.52) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658157-A1 | DIARYL PIPERAZINOACETAMIDE COMPOUNDS AS ANTIMUSCARINIC AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-06-21 | — | — | EP | disclosed |
| WO-1994005648-A1 | DIARYL PIPERAZINOACETAMIDE COMPOUNDS AS ANTIMUSCARINIC AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-17 | — | — | WO | disclosed |
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |