Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 2/20 | 0.48 |
| ▸ | CMA1 | P23946 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346551 | 1.00 | CTSG (0.48) | CTSGCMA1ALDH1A1POLBRAB9A | |
| SCHEMBL7301724 | 0.91 | PSMB5 (0.47) | CTSLCTSB | |
| SCHEMBL7301731 | 0.91 | PSMB5 (0.47) | CTSLCTSB | |
| SCHEMBL7301741 | 0.91 | PSMB5 (0.47) | CTSLCTSB | |
| SCHEMBL7347976 | 0.89 | ALDH1A1 (0.45) | CTSGCMA1ALDH1A1POLBRAB9A | |
| SCHEMBL7342545 | 0.86 | PSMB5 (0.47) | ALDH1A1POLBRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7342540 | 0.86 | PSMB5 (0.47) | ALDH1A1POLBRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7343844 | 0.86 | HPGD (0.53) | ALDH1A1POLBRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7312135 | 0.85 | CTSG (0.46) | CTSGCMA1SMN1; SMN2CTSLCTSB | |
| SCHEMBL7312126 | 0.85 | CTSG (0.46) | CTSGCMA1SMN1; SMN2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603873-B1 | Aminoketone derivatives | MITSUBISHI CHEM CORP (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5424325-A | Inibitors of thiol protease and may be used as therapeutic agents for treating muscular dystrophy, cataracts, strokes | MITSUBISHI KASEI CORPORATION (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0603873-A1 | Aminoketone derivatives | Mitsubishi Chemical Corporation (JP) | 1994-06-29 | — | — | EP | disclosed |