SCHEMBL7346703

SCHEMBL7346703

O=[C]Oc1noc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.47
MGLL Q99685 1/20 0.47
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
MAOB P27338 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.39
TP53 P04637 4/20 0.39
HIF1A Q16665 6/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6972027 0.75 FAAH (0.51) FAAHMGLLCA12CA1CA2
SCHEMBL8142563 0.75 FAAH (0.56) FAAHMGLLCA12CA1CA2
SCHEMBL14775860 0.73 HIF1A (0.47) FAAHMGLLCA12CA1CA2
SCHEMBL9035692 0.72 FAAH (0.49) FAAHMGLLCA12CA1CA2
SCHEMBL25255597 0.71 FAAH (0.49) FAAHMGLLSMN1; SMN2TP53HIF1A
SCHEMBL10520166 0.71 FAAH (0.45) FAAHMGLLCA12CA1CA2
SCHEMBL28970339 0.71 FAAH (0.49) FAAHMGLLCA12CA1CA2
SCHEMBL225286 0.71 MAOB (0.44) FAAHMGLLCA12CA1CA2
SCHEMBL10733456 0.70 FAAH (0.59) FAAHMGLLCA12CA1CA2
SCHEMBL7814843 0.70 FAAH (0.51) FAAHMGLLCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117693500-A Carboxamide derivative and agricultural/horticultural plant disease control agent 组合化学工业株式会社 2024-03-12 CN disclosed
WO-2023286855-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT クミアイ化学工業株式会社 2023-01-19 WO disclosed
US-5912352-A CATALYTIC REDUCTION OF HYDRAZIDE TO HYDRAZINE DERIVATIVE IN PRESENCE OF COMPLEX HYDRIDE; ACYL MIGRATION; HYDROGENATION; CATALYST SELECTIVITY NOVARTIS FINANCE CORPORATION (US) 1999-06-15 US disclosed
WO-1997046514-A1 PROCESS FOR THE PREPARATION OF HYDRAZINE DERIVATIVES USEFUL AS INTERMEDIATES FOR THE PREPARATION OF PEPTIDE ANALOGUES NOVARTIS AG (CH) 1997-12-11 WO disclosed