Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14427253 | 0.85 | MAPT (0.47) | HIF1AFAAHMGLLALDH1A1KMT2A | |
| SCHEMBL25255597 | 0.84 | FAAH (0.49) | HIF1AFAAHMGLLALDH1A1KMT2A | |
| SCHEMBL10520166 | 0.84 | FAAH (0.45) | HIF1AFAAHMGLLALDH1A1KMT2A | |
| SCHEMBL70238 | 0.83 | SMN1; SMN2 (0.45) | HIF1AFAAHMGLLALDH1A1KMT2A | |
| SCHEMBL28103593 | 0.80 | ALDH1A1 (0.46) | HIF1AFAAHMGLLALDH1A1KMT2A | |
| SCHEMBL68963 | 0.79 | HIF1A (0.50) | HIF1AFAAHMGLLALDH1A1KMT2A | |
| SCHEMBL5649712 | 0.79 | KMT2A (0.50) | HIF1AFAAHMGLLALDH1A1KMT2A | |
| SCHEMBL10659456 | 0.78 | FAAH (0.54) | HIF1AFAAHMGLLALDH1A1TP53 | |
| SCHEMBL9035692 | 0.74 | FAAH (0.49) | HIF1AFAAHMGLLALDH1A1KMT2A | |
| SCHEMBL6988473 | 0.74 | FAAH (0.43) | HIF1AFAAHMGLLALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318367-B1 | PIPERIDINE AND PYRROLIDINE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-03-20 | — | — | EP | claimed |