Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775860 | 0.84 | HIF1A (0.47) | FAAHMGLLALDH1A1KMT2AHIF1A | |
| SCHEMBL10520166 | 0.83 | FAAH (0.45) | FAAHMGLLALDH1A1KMT2AHIF1A | |
| SCHEMBL28103593 | 0.82 | ALDH1A1 (0.46) | FAAHMGLLALDH1A1KMT2AHIF1A | |
| SCHEMBL70238 | 0.81 | SMN1; SMN2 (0.45) | FAAHMGLLALDH1A1KMT2AHIF1A | |
| SCHEMBL14427253 | 0.80 | MAPT (0.47) | FAAHMGLLALDH1A1KMT2AHIF1A | |
| SCHEMBL9036820 | 0.79 | FAAH (0.51) | FAAHALDH1A1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL68963 | 0.78 | HIF1A (0.50) | FAAHMGLLALDH1A1KMT2AHIF1A | |
| SCHEMBL5649712 | 0.77 | KMT2A (0.50) | FAAHMGLLALDH1A1KMT2AHIF1A | |
| SCHEMBL8142563 | 0.76 | FAAH (0.56) | FAAHMGLLALDH1A1HIF1ATP53 | |
| SCHEMBL10659456 | 0.73 | FAAH (0.54) | FAAHMGLLALDH1A1HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534442-B2 | Benzisoxazole derivative | Sumitomo Pharma Co., Ltd. (JP) | 2026-01-27 | — | — | US | disclosed |
| US-20230202991-A1 | BENZISOXAZOLE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-06-29 | — | — | US | disclosed |
| CN-115836058-A | Benzisoxazole derivatives | 住友制药株式会社 | 2023-03-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202991-A1 | BENZISOXAZOLE DERIVATIVE | HDAC3, GABRA5, HDAC2 | FAAH 1628/4885MGLL 4094/4885ALDH1A1 353/4885 |
| US-12534442-B2 | Benzisoxazole derivative | GABRA6, SLC6A1, GABRA1 | FAAH 247/4885MGLL 2687/4885ALDH1A1 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.