Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444781 | 0.82 | ACHE (0.42) | CA12CA1CA2CA9ACHE | |
| SCHEMBL2441052 | 0.76 | FAAH (0.42) | FAAHMGLLCA12CA1CA2 | |
| SCHEMBL6972027 | 0.76 | FAAH (0.51) | FAAHMGLLCA12CA1CA2 | |
| SCHEMBL8142563 | 0.76 | FAAH (0.56) | FAAHMGLLCA12CA1CA2 | |
| SCHEMBL14775860 | 0.74 | HIF1A (0.47) | FAAHMGLLCA12CA1CA2 | |
| SCHEMBL7814843 | 0.72 | FAAH (0.51) | FAAHMGLLCA12CA1CA2 | |
| SCHEMBL10733456 | 0.72 | FAAH (0.59) | FAAHMGLLCA12CA1CA2 | |
| SCHEMBL8373116 | 0.72 | FAAH (0.69) | FAAHMGLLCA12CA1CA2 | |
| SCHEMBL7346703 | 0.72 | FAAH (0.47) | FAAHMGLLCA12CA1CA2 | |
| SCHEMBL7257058 | 0.72 | MAPT (0.44) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442655-B1 | Benzisoxazole derivatives | ZENECA LTD (GB) | 1996-01-17 | — | — | EP | disclosed |
| US-5176737-A | BENZISOXAZOLE COMPOUNDS USEFUL AS HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-05 | — | — | US | disclosed |
| EP-0442655-A2 | Benzisoxazole derivatives | ZENECA LIMITED (GB) | 1991-08-21 | — | — | EP | disclosed |
| US-4571255-A | Subsituted phenoxybenzisoxazole herbicides | PPG INDUSTRIES, INC. (US) | 1986-02-18 | — | — | US | disclosed |
| US-4571255-A | Subsituted phenoxybenzisoxazole herbicides | PPG INDUSTRIES, INC. (US) | 1986-02-18 | — | — | US | disclosed |
| US-4571255-A | Subsituted phenoxybenzisoxazole herbicides | PPG INDUSTRIES, INC. (US) | 1986-02-18 | — | — | US | disclosed |