Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608369 | 0.89 | L3MBTL1 (0.41) | L3MBTL1TDP1PPARGMEN1KMT2A | |
| SCHEMBL7346161 | 0.89 | L3MBTL1 (0.58) | L3MBTL1TDP1ABCB1SLC6A5CALM1 | |
| SCHEMBL7778557 | 0.82 | L3MBTL1 (0.53) | L3MBTL1TDP1ABCB1SLC6A5CALM1 | |
| SCHEMBL7347241 | 0.81 | L3MBTL1 (0.51) | L3MBTL1TDP1ABCB1SLC6A5MEN1 | |
| SCHEMBL293291 | 0.75 | L3MBTL1 (0.57) | L3MBTL1TDP1ABCB1SLC6A5ALDH1A1 | |
| SCHEMBL19210361 | 0.75 | L3MBTL1 (0.88) | L3MBTL1TDP1ABCB1CALM1MEN1 | |
| SCHEMBL7889248 | 0.74 | L3MBTL1 (0.55) | L3MBTL1TDP1CALM1MEN1KMT2A | |
| SCHEMBL7336817 | 0.73 | LMNA (0.41) | KMT2AALDH1A1LMNA | |
| SCHEMBL2449734 | 0.72 | LIPG (0.49) | PPARGKMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL4154352 | 0.72 | L3MBTL1 (0.55) | L3MBTL1TDP1ABCB1CALM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |