Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608367 | 0.88 | RAB9A (0.43) | L3MBTL1TDP1ALDH1A1KMT2AHPGD | |
| SCHEMBL7778557 | 0.85 | L3MBTL1 (0.53) | L3MBTL1TDP1ALDH1A1KMT2ANPC1 | |
| SCHEMBL7346161 | 0.81 | L3MBTL1 (0.58) | L3MBTL1TDP1ALDH1A1KMT2ASLC6A5 | |
| SCHEMBL7347243 | 0.81 | L3MBTL1 (0.53) | L3MBTL1TDP1ALDH1A1KMT2ASLC6A5 | |
| SCHEMBL29026477 | 0.79 | LTA4H (0.49) | L3MBTL1TDP1ALDH1A1KMT2AHPGD | |
| SCHEMBL293291 | 0.79 | L3MBTL1 (0.57) | L3MBTL1TDP1ALDH1A1NPC1SLC6A5 | |
| SCHEMBL19210361 | 0.73 | L3MBTL1 (0.88) | L3MBTL1TDP1ALDH1A1KMT2AABCB1 | |
| SCHEMBL7336813 | 0.72 | FOLH1 (0.40) | ALDH1A1 | |
| SCHEMBL28284271 | 0.72 | TSHR (0.42) | L3MBTL1TDP1ALDH1A1HPGDTP53 | |
| SCHEMBL14339781 | 0.71 | CALM1 (0.53) | ALDH1A1NPC1SLC6A5USP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |