Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7338746 | 0.99 | POLB (0.42) | POLBNAMPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL7346648 | 0.91 | GAA (0.47) | POLBKMT2AMEN1 | |
| SCHEMBL7335641 | 0.90 | NAMPT (0.41) | POLBNAMPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL7368219 | 0.90 | L3MBTL1 (0.45) | POLBNAMPTRAB9AALDH1A1KMT2A | |
| SCHEMBL7748299 | 0.90 | NAMPT (0.44) | POLBNAMPT | |
| SCHEMBL7347838 | 0.89 | POLB (0.44) | POLBNAMPTRAB9AALDH1A1HPGD | |
| SCHEMBL7338325 | 0.89 | POLB (0.40) | POLBNAMPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL7373469 | 0.88 | L3MBTL1 (0.40) | POLBNAMPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7346264 | 0.88 | POLB (0.43) | POLBNAMPTRAB9AALDH1A1HPGD | |
| SCHEMBL7338872 | 0.87 | POLB (0.43) | POLBNAMPTRAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |