Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368219 | 0.92 | L3MBTL1 (0.45) | NAMPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL7748299 | 0.91 | NAMPT (0.44) | NAMPTPOLB | |
| SCHEMBL7347340 | 0.90 | POLB (0.43) | NAMPTPOLBKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7338746 | 0.90 | POLB (0.42) | NAMPTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL7373469 | 0.90 | L3MBTL1 (0.40) | NAMPTPOLBLMNAALDH1A1 | |
| SCHEMBL7346648 | 0.89 | GAA (0.47) | POLBMEN1KMT2A | |
| SCHEMBL7345845 | 0.88 | RAB9A (0.42) | NAMPTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL7375729 | 0.88 | AVPR2 (0.41) | NAMPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7373631 | 0.87 | NAMPT (0.43) | NAMPTPOLBKDM4EKMT2AALDH1A1 | |
| SCHEMBL7338325 | 0.87 | POLB (0.40) | NAMPTPOLBKDM4EKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |