Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373469 | 0.94 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1NAMPTPOLB | |
| SCHEMBL7335641 | 0.92 | NAMPT (0.41) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7748299 | 0.91 | NAMPT (0.44) | L3MBTL1GAANAMPTPOLB | |
| SCHEMBL7347340 | 0.90 | POLB (0.43) | KMT2AMEN1RAB9AALDH1A1NAMPT | |
| Hydrochloric Acid SCHEMBL7338746 | 0.90 | POLB (0.42) | KMT2AMEN1RAB9AALDH1A1NAMPT | |
| SCHEMBL7375729 | 0.89 | AVPR2 (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2NAMPT | |
| SCHEMBL7346648 | 0.89 | GAA (0.47) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL7373631 | 0.87 | NAMPT (0.43) | KMT2AALDH1A1GAANAMPTPOLB | |
| SCHEMBL7367751 | 0.87 | AVPR2 (0.40) | ALDH1A1NAMPT | |
| SCHEMBL7338325 | 0.87 | POLB (0.40) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |