Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335641 | 0.91 | NAMPT (0.41) | NAMPTPOLB | |
| SCHEMBL7368219 | 0.91 | L3MBTL1 (0.45) | NAMPTPOLBGAAL3MBTL1 | |
| SCHEMBL7347340 | 0.90 | POLB (0.43) | NAMPTPOLB | |
| Hydrochloric Acid SCHEMBL7338746 | 0.89 | POLB (0.42) | NAMPTPOLB | |
| SCHEMBL7373469 | 0.89 | L3MBTL1 (0.40) | NAMPTPOLBL3MBTL1HTR1A | |
| SCHEMBL7346648 | 0.88 | GAA (0.47) | POLBGAA | |
| SCHEMBL7375729 | 0.87 | AVPR2 (0.41) | NAMPT | |
| SCHEMBL7373631 | 0.86 | NAMPT (0.43) | NAMPTPOLBGAA | |
| SCHEMBL7338325 | 0.86 | POLB (0.40) | NAMPTPOLBGAAL3MBTL1 | |
| SCHEMBL7367751 | 0.85 | AVPR2 (0.40) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |