Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910771 | 0.89 | NOTUM (0.41) | NOTUMRIOK2 | |
| SCHEMBL8911334 | 0.87 | PDE3B (0.40) | PDE3BPDE3ARIOK2 | |
| SCHEMBL8911357 | 0.80 | ALDH1A1 (0.43) | — | |
| SCHEMBL2951073 | 0.78 | GRIA1 (0.56) | NOTUMPDE3BPDE3AFGFR3PIK3R1 | |
| SCHEMBL7347889 | 0.77 | PARP1 (0.39) | — | |
| SCHEMBL8186584 | 0.77 | GRIA1 (0.37) | NOTUMPDE3BPDE3A | |
| SCHEMBL8912871 | 0.77 | NOTUM (0.39) | NOTUM | |
| SCHEMBL8912056 | 0.77 | GRIA1 (0.48) | — | |
| SCHEMBL8186930 | 0.76 | PDE5A (0.42) | NOTUM | |
| SCHEMBL8911468 | 0.76 | GRIA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698024-B1 | [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-01-22 | — | — | EP | claimed |
| EP-0698024-B1 | [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-01-22 | — | — | EP | disclosed |
| US-5532236-A | TREATMENT OF PARKINSON'S DISEASE | NOVO NORDISK A/S (DK) | 1996-07-02 | — | — | US | disclosed |