Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 14/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338162 | 0.87 | MME (0.56) | CACNA1BIL1RNERAP2ERAP1 | |
| SCHEMBL7366026 | 0.84 | ITGA4 (0.55) | ITGA4ITGB1 | |
| SCHEMBL7366029 | 0.84 | ITGA4 (0.55) | ITGA4ITGB1 | |
| SCHEMBL7340357 | 0.83 | ITGA4 (0.57) | ITGA4ITGB1 | |
| SCHEMBL7340367 | 0.83 | ITGA4 (0.57) | ITGA4ITGB1 | |
| SCHEMBL7344054 | 0.82 | CACNA1B (0.51) | ITGA4MMP1ITGB1CACNA1B | |
| SCHEMBL7348198 | 0.80 | ITGA4 (0.51) | ITGA4ITGB1 | |
| SCHEMBL7346037 | 0.79 | IL1RN (0.53) | CACNA1BIL1RNERAP2ERAP1 | |
| SCHEMBL7339698 | 0.79 | IL1RN (0.53) | CACNA1BIL1RNERAP2ERAP1 | |
| SCHEMBL7343134 | 0.78 | MMP1 (0.52) | MMP1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |