Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301814 | 0.88 | KMT2A (0.40) | HSD11B1PPARAMMP2MMP13MMP1 | |
| SCHEMBL7313763 | 0.88 | NR1I2 (0.37) | HSD11B1PPARAMMP2MMP13MMP1 | |
| SCHEMBL1128629 | 0.69 | POLB (0.42) | HSD11B1CYP2C19HIF1A | |
| SCHEMBL3707552 | 0.68 | PPARG (0.44) | HSD11B1PPARAPPARGCYP2C19MEN1 | |
| SCHEMBL7304270 | 0.67 | KCNN4 (0.43) | HSD11B1CYP2C19HIF1AKMT2A | |
| SCHEMBL7348556 | 0.67 | KMT2A (0.44) | HSD11B1CYP2C19HIF1AMEN1KMT2A | |
| SCHEMBL10763284 | 0.66 | KCNN4 (0.41) | ALOX15PPARGMEN1KMT2A | |
| SCHEMBL27582686 | 0.65 | KMT2A (0.57) | MMP2MMP13ALOX15PPARGCYP2C19 | |
| Acetic Acid SCHEMBL29119752 | 0.65 | ALDH1A1 (0.41) | PPARAMMP2MMP13MMP1ALOX15 | |
| SCHEMBL831034 | 0.65 | HPGD (0.51) | MMP2ALOX15CYP2C19MMP7MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931788-B1 | Metalloprotease inhibitors | PFIZER LTD (GB) | 2002-11-06 | — | — | EP | disclosed |