Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348241 | 0.88 | HSD11B1 (0.38) | KMT2AMEN1MMP2MMP13MMP1 | |
| SCHEMBL7313763 | 0.85 | NR1I2 (0.37) | MMP2MMP13MMP1PPARAHSD11B1 | |
| SCHEMBL7348556 | 0.80 | KMT2A (0.44) | KMT2AMEN1HSD11B1MAPTALDH1A1 | |
| SCHEMBL7313045 | 0.72 | HSD11B1 (0.39) | KMT2AMEN1MMP2MMP13MMP1 | |
| SCHEMBL21393560 | 0.69 | ALDH1A1 (0.38) | MAPTALDH1A1 | |
| SCHEMBL4401320 | 0.67 | CA1 (0.50) | KMT2AMEN1MAPTALDH1A1 | |
| Acetic Acid SCHEMBL29119752 | 0.67 | ALDH1A1 (0.41) | KMT2AMEN1MMP2MMP13MMP1 | |
| SCHEMBL11279744 | 0.67 | KMT2A (0.50) | KMT2AMEN1PPARAHSD11B1PPARG | |
| SCHEMBL2822682 | 0.67 | PPARA (0.54) | KMT2AMEN1PPARAHSD11B1PPARG | |
| SCHEMBL3707552 | 0.66 | PPARG (0.44) | KMT2AMEN1PPARAHSD11B1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931788-B1 | Metalloprotease inhibitors | PFIZER LTD (GB) | 2002-11-06 | — | — | EP | disclosed |
| US-6090852-A | MATRIX METALLOPROTEASE INHIBITOR | PFIZER INC (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0931788-A2 | Metalloprotease inhibitors | Pfizer Limited (GB) | 1999-07-28 | — | — | EP | disclosed |