Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28621039 | 0.81 | CA12 (0.76) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL8746688 | 0.78 | LMNA (0.58) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL6228523 | 0.78 | MAPT (0.65) | LMNAMAPTPTGS2 | |
| SCHEMBL2081746 | 0.76 | MAPT (0.71) | LMNAMAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL10553766 | 0.76 | LMNA (0.56) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL6445603 | 0.76 | LMNA (0.56) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL28049501 | 0.76 | LMNA (0.56) | LMNAMAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL10553753 | 0.76 | LMNA (0.56) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL9570575 | 0.76 | DRD2 (0.65) | LMNAMAPTPTGS2 | |
| SCHEMBL8948956 | 0.75 | CA12 (0.68) | LMNAMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153589-A | FOR TREATING VIRAL INFECTIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-11-28 | — | — | US | disclosed |
| US-5190969-A | Epoxy derivatives of amino acids as viricides for treatment of HIV infections | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1993-03-02 | — | — | US | disclosed |
| US-5104892-A | N-heteroalkyl substitutes 1-aryloxy-2-propanolamine | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-14 | — | — | US | disclosed |
| WO-1991009023-A1 | N-HETEROARALKYL-SUBSTITUTED 1-ARYLOXY-2-PROPANOLAMINE AND PROPYLAMINE DERIVATIVES POSSESSING CLASS III ANTIARRHYTHMIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-27 | — | — | WO | disclosed |