Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 5/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357801 | 0.78 | MMP8 (0.45) | MMP8KDM5APHF8KDM4C | |
| SCHEMBL7349299 | 0.78 | MMP8 (0.38) | MMP8EPHX1PLA2G10CA1CA2 | |
| SCHEMBL7349646 | 0.75 | CSNK1E (0.44) | EPHX1 | |
| SCHEMBL7357535 | 0.75 | CSNK1E (0.44) | EPHX1 | |
| SCHEMBL6894680 | 0.72 | KDM5A (0.43) | KDM5APHF8KDM4CCES2KDM5C | |
| SCHEMBL23142575 | 0.70 | CA1 (0.40) | MMP8EPHX1CA1CA2 | |
| SCHEMBL9074168 | 0.70 | SPHK1 (0.39) | KDM5APHF8KDM4CCES2 | |
| SCHEMBL7825058 | 0.69 | KDM5A (0.42) | KDM5APHF8KDM4CCES2KDM5C | |
| SCHEMBL8766997 | 0.69 | GPR84 (0.39) | EPHX1PLA2G2ACA1CA2 | |
| SCHEMBL5495278 | 0.69 | KDM5A (0.36) | KDM5APHF8KDM4CCA1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009736-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | Roche Diagnostics GmbH (DE) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999011608-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-03-11 | — | — | WO | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |