Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360512 | 0.83 | L3MBTL1 (0.35) | MMP8MMP3 | |
| SCHEMBL7348722 | 0.78 | MMP8 (0.40) | MMP8CA2CA1EPHX1PLA2G10 | |
| SCHEMBL7353864 | 0.78 | CSNK1E (0.48) | MMP3 | |
| SCHEMBL7359568 | 0.76 | CSNK1E (0.43) | — | |
| SCHEMBL8601943 | 0.70 | GPR84 (0.50) | CA2CA1EPHX1LCKPPARD | |
| SCHEMBL8603095 | 0.70 | GPR84 (0.50) | CA2CA1EPHX1LCKPPARD | |
| SCHEMBL10499515 | 0.70 | GPR84 (0.50) | CA2CA1EPHX1LCKPPARD | |
| SCHEMBL8626076 | 0.70 | GPR84 (0.50) | CA2CA1EPHX1LCKPPARD | |
| SCHEMBL9000227 | 0.70 | GPR84 (0.50) | CA2CA1EPHX1LCKPPARD | |
| SCHEMBL8600274 | 0.70 | GPR84 (0.50) | CA2CA1EPHX1LCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009736-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | Roche Diagnostics GmbH (DE) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999011608-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-03-11 | — | — | WO | disclosed |