Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.51 |
| ▸ | MMP9 | P14780 | 11/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348004 | 0.92 | HDAC7 (0.48) | MMP2MMP9CA12CA9ALDH1A1 | |
| SCHEMBL7342937 | 0.89 | HDAC1 (0.52) | MMP2MMP9ALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL7080833 | 0.86 | ALDH1A1 (0.58) | MMP2MMP9CA12CA9ALDH1A1 | |
| SCHEMBL7342436 | 0.80 | MMP2 (0.52) | MMP2MMP9CA12CA9ALDH1A1 | |
| SCHEMBL1286243 | 0.76 | ALDH1A1 (0.55) | MMP2MMP9CA12CA9ALDH1A1 | |
| SCHEMBL1781793 | 0.76 | ALDH1A1 (0.55) | MMP2MMP9CA12CA9ALDH1A1 | |
| SCHEMBL10968367 | 0.76 | MMP2 (0.50) | MMP2MMP9CA12CA9ALDH1A1 | |
| SCHEMBL7079889 | 0.76 | MMP2 (0.49) | MMP2MMP9CA12CA9ALDH1A1 | |
| SCHEMBL20556320 | 0.75 | MMP2 (0.51) | MMP2MMP9ALDH1A1MAPTNPSR1 | |
| SCHEMBL7350594 | 0.75 | MEN1 (0.33) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833150-A | HYPOTENSIVES, ANTIARRHYTHMIA AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4652573-A | HYPOTENSIVE AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0194685-A1 | 1,4-Dihydropyridines | Whitby Research Incorporated (US) | 1986-09-17 | — | — | EP | disclosed |