Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351979 | 0.87 | DRD2 (0.44) | CYP1A2CYP2D6ACKR3HTR1A | |
| SCHEMBL7353206 | 0.87 | DRD2 (0.46) | CYP1A2CYP2D6ACKR3HTR1A | |
| SCHEMBL7344193 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KMT2AGFERCYP1A2CYP2D6 | |
| SCHEMBL12123632 | 0.81 | DRD2 (0.54) | ALDH1A1KMT2AGFERCYP1A2CYP2D6 | |
| SCHEMBL7348412 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1KMT2AGFERCYP1A2CYP2D6 | |
| SCHEMBL12123643 | 0.80 | ESR1 (0.53) | ALDH1A1KMT2AGFERCYP1A2CYP2D6 | |
| SCHEMBL7352747 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KMT2AHSD17B10ACKR3MEN1 | |
| SCHEMBL11479683 | 0.76 | DRD2 (0.51) | KMT2AMEN1HTR1AMAOB | |
| SCHEMBL21780538 | 0.75 | F2R (0.56) | ALDH1A1KMT2AHSD17B10ACKR3MEN1 | |
| SCHEMBL22097313 | 0.75 | PKM (0.49) | ALDH1A1KMT2ACYP1A2CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |