Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30876366 | 0.83 | ALDH1A1 (0.53) | SMN1; SMN2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL19317367 | 0.83 | ALDH1A1 (0.53) | SMN1; SMN2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL7344872 | 0.82 | MCL1 (0.49) | SMN1; SMN2KMT2AHPGDLMNAMAPK1 | |
| SCHEMBL6838793 | 0.82 | MCL1 (0.66) | SMN1; SMN2KMT2AHPGDLMNAALOX15 | |
| SCHEMBL7450174 | 0.82 | BRAF (0.50) | KMT2AALDH1A1MEN1 | |
| SCHEMBL16479304 | 0.80 | OGG1 (0.56) | SMN1; SMN2KMT2AHPGDLMNATSHR | |
| SCHEMBL17967806 | 0.79 | BCHE (0.48) | SMN1; SMN2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL6016227 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL778673 | 0.78 | MEN1 (0.52) | SMN1; SMN2KMT2ATSHRALDH1A1MEN1 | |
| SCHEMBL7343296 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932582-A | Fibrinogen receptor antagonist prodrugs | MERCK & CO., INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0912513-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000401-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |