Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342234 | 0.86 | ITGB3 (0.59) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| SCHEMBL7347645 | 0.84 | F2 (0.58) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| Iodomethane SCHEMBL9367655 | 0.84 | ITGB3 (0.57) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| SCHEMBL7356492 | 0.80 | F2 (0.52) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| SCHEMBL25409382 | 0.79 | GAA (0.49) | KDM4ELMNAGAAMAPTALOX15 | |
| SCHEMBL7353174 | 0.75 | F2 (0.49) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| SCHEMBL7336222 | 0.75 | ITGB3 (0.46) | ITGB3ITGA2BKDM4ELMNAGAA | |
| SCHEMBL7441356 | 0.73 | ITGB3 (0.57) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| SCHEMBL23384130 | 0.72 | ALDH1A1 (0.54) | KDM4ELMNAGAAMAPT | |
| SCHEMBL7352886 | 0.72 | ITGB3 (0.49) | PRSS1PRSS2PRSS3F2TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637304-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022303-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1993-11-11 | — | — | WO | disclosed |