Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356492 | 0.87 | F2 (0.52) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7355673 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBGAATDP1ALDH1A1 | |
| SCHEMBL7346169 | 0.86 | UBE2T (0.43) | ITGB3ITGA2B | |
| SCHEMBL7352886 | 0.83 | ITGB3 (0.49) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7353169 | 0.82 | ITGB3 (0.53) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL9371212 | 0.80 | ITGB3 (0.50) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7358257 | 0.80 | ITGB3 (0.71) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL9179090 | 0.75 | ITGB3 (0.46) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7352203 | 0.75 | PRSS1 (0.51) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7344477 | 0.74 | ITGB3 (0.72) | F2PRSS1PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637304-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1995-02-08 | — | — | EP | claimed |
| WO-1993022303-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1993-11-11 | — | — | WO | claimed |
| EP-0637304-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022303-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1993-11-11 | — | — | WO | disclosed |