Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354615 | 0.89 | NOTUM (0.44) | DRD3PARP1ABCB1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7355986 | 0.87 | SIGMAR1 (0.44) | DRD3MAPTKDM4EKMT2AHSD17B10 | |
| SCHEMBL7354812 | 0.86 | KDM4E (0.42) | PARP1MAPTKDM4EKMT2AHSD17B10 | |
| SCHEMBL7360674 | 0.86 | CYP2C19 (0.42) | DRD3PARP1MAPTKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7354409 | 0.86 | KDM4E (0.42) | PARP1MAPTKDM4EKMT2AHSD17B10 | |
| SCHEMBL7354626 | 0.85 | KDM4E (0.43) | PARP1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7360642 | 0.85 | HTR1A (0.41) | DRD3PARP1MAPTKDM4EKMT2A | |
| SCHEMBL7355443 | 0.84 | KDM4E (0.42) | DRD3PARP1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7361126 | 0.84 | KMT2A (0.42) | DRD3PARP1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7360192 | 0.84 | KDM4E (0.42) | PARP1MAPTKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |