Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360674 | 0.92 | CYP2C19 (0.42) | NOTUMNPC1RAB9AKDM4EGAA | |
| SCHEMBL7351996 | 0.91 | ALDH1A1 (0.42) | NOTUMNPC1RAB9AKDM4EPARP1 | |
| Hydrochloric Acid SCHEMBL7360641 | 0.90 | PARP1 (0.42) | NPC1RAB9AKDM4EGAAPARP1 | |
| SCHEMBL7360194 | 0.89 | MAPT (0.43) | NPC1RAB9AKDM4ETSHRMAPT | |
| SCHEMBL7352476 | 0.89 | DRD3 (0.43) | KDM4EGAAPARP1ABCB1USP2 | |
| SCHEMBL7355377 | 0.88 | SMN1; SMN2 (0.44) | KDM4EL3MBTL1USP2MAPTMEN1 | |
| SCHEMBL7354626 | 0.88 | KDM4E (0.43) | NPC1RAB9AKDM4EPARP1HSD17B10 | |
| SCHEMBL7357135 | 0.87 | KDM4E (0.42) | NOTUMNPC1RAB9AKDM4EGAA | |
| SCHEMBL7355443 | 0.87 | KDM4E (0.42) | KDM4EPARP1HSD17B10MAPTDRD3 | |
| SCHEMBL7360192 | 0.87 | KDM4E (0.42) | KDM4EPARP1HSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |