Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351996 | 0.93 | ALDH1A1 (0.42) | KDM4EMAPTNPC1RAB9ANOTUM | |
| SCHEMBL7354615 | 0.92 | NOTUM (0.44) | KDM4EMAPTDRD3NPC1RAB9A | |
| SCHEMBL7360194 | 0.91 | MAPT (0.43) | CYP2C19KDM4EMAPTLMNAHTR1A | |
| SCHEMBL7354626 | 0.91 | KDM4E (0.43) | KDM4EMAPTLMNAHTR1ANPC1 | |
| Hydrochloric Acid SCHEMBL7360641 | 0.91 | PARP1 (0.42) | KDM4EMAPTHTR1ANPC1RAB9A | |
| SCHEMBL7355443 | 0.90 | KDM4E (0.42) | KDM4EMAPTDRD3LMNAHTR1A | |
| SCHEMBL7360192 | 0.90 | KDM4E (0.42) | KDM4EMAPTLMNAHTR1ASIGMAR1 | |
| SCHEMBL7355377 | 0.90 | SMN1; SMN2 (0.44) | KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL7355373 | 0.89 | KDM4E (0.42) | KDM4EMAPTLMNAHTR1ASIGMAR1 | |
| SCHEMBL7353274 | 0.89 | KDM4E (0.42) | KDM4EMAPTDRD3LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |