Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353255 | 0.83 | ELANE (0.35) | ELANEDGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL29657305 | 0.83 | CA4 (0.40) | ELANEDGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL30114986 | 0.83 | ELANE (0.35) | ELANEDGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL3390385 | 0.82 | CTSK (0.30) | — | |
| SCHEMBL9014674 | 0.80 | CYP1A2 (0.30) | CYP2D6 | |
| SCHEMBL30973572 | 0.79 | ELANE (0.33) | ELANEDGAT1HDAC6HDAC1HDAC2 | |
| SCHEMBL30918746 | 0.76 | FDPS (0.36) | ELANEDGAT1 | |
| SCHEMBL29121 | 0.73 | DGAT1 (0.46) | ELANECA2DGAT1CA1CA7 | |
| SCHEMBL11161628 | 0.72 | — | — | |
| SCHEMBL25472070 | 0.70 | CA2 (0.35) | ELANECA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018188-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL[B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | THE UPJOHN COMPANY (US) | 1994-08-18 | — | — | WO | disclosed |